Production Cost Report | Healthcare

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Artesunate Production Cost Breakup From Artemisinin

Details: Germany - based plant Q1 2024  | From $ USD

This report entails the detailed cost evaluation of artesunate production from artemisinin. The preparation process begins with the chemical reaction between artemisinin and a reducing agent, such as sodium borohydride or potassium borohydride, followed by an esterification reaction. The product undergoes esterification with succinic anhydride and results in the production of artesunate as the final product.

Top Producers of Artesunate

  • Fosun Pharma
  • Ipca Laboratories
  • Acino
  • MCW Healthcare
  • Sanofi Aventis

Feedstocks for Artesunate

Artesunate is an organic chemical ester obtained by using artemisinin, sodium or potassium borohydride, and succinic anhydride as its major feedstocks. The procurement of artesunate and its feedstock is mainly influenced by various factors such as the availability of its raw materials (including boron trifluoride, sodium hydride, etc.), stability in the supply chain, production cost, market prices, logistics, and trade activities, etc. Moreover, factors, including its demand in the pharmaceutical and chemical industries, activities in its upstream industries, trade, and governmental policies, have a significant role to play in governing its overall procurement in the global chemical market.

The project economic analysis provided in the report discusses a Germany-based plant:

  • Manufacturing Process
    • Process Flow
    • Material Flow
    • Material Balance
  • Raw Material and Product's Specifications
    • Raw Material Consumption
    • Product and Co-Product Generation
    • Capital Investment
  • Land and Site Cost
    • Offsites/Civil Works
    • Equipment Cost
    • Auxiliary Equipment Cost
    • Contingency
    • Engineering and Consulting Charges
    • Working Capital
  • Variable Cost
    • Raw Material
    • Utilities
  • Fixed Cost
    • Labor Requirement & Wages
    • Overhead Expenses
    • Maintenance Charges
  • Financing Costs
    • Interest on Working Capital
    • Interest on Loans
  • Depreciation Charges
  • General Sales and Admin Costs
  • Production Cost Summary
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Report Content

Key Process Information

Evaluation of significant technical parameters along with process descriptions such as:

  • Consumption of Raw Material
  • Product Creation
  • Block Flow Diagram
  • Description of the Manufacturing Facility

Utilities Consumption

Evaluation of utilities consumed during the entire process based on:

  • Consumption per unit of product generated
  • Utility cost split and share of each utility in the total cost

Process Flow Diagram

Representation of various operations involved including:

  • Step-wise process
  • Utility consumption in each operation

Capital Cost Analysis

In-depth analysis of costs involved in setting up a new manufacturing unit, including:

  • Cost of Building a Process Unit
  • Cost of Setting Up the Infrastructure
  • Working Capital
  • Commissioning & Start-Up of the Plant

Implementation Schedule

Time frame of the project design, which includes:

  • Plant Start-Up
  • Plant Construction
  • Engineering Fundamentals
  • Raw Material Procurement

Construction Cost Details

Detailed analysis of costs involved in the operation of various functional units in the process unit and infrastructure.

Operating Cost Analysis

Evaluation of costs associated with the production of the final product, namely:

  • Procurement of Raw Materials
  • Consumption of Utilities
  • Fixed Costs
  • Depreciation

Economic Analysis

Analysis of the way in which process economics are impacted by plant capacity.

  • Construction Cost
  • Working Capital
  • Fixed and Variable Operating Costs
  • Corporate Overhead
  • Depreciation

Customized Analyses

Detailed cost estimates of any industrial plant depending on your requirements, including plant capacity and location as per the need.

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