This study analyzes Ivermectin Production by Hydrogenation Reaction, covering manufacturing, process flow, operating expenses, and financial considerations.
Last Updated: January, 2025
This report entails the detailed cost evaluation of ivermectin production by hydrogenation reaction. The preparation process begins by fermenting Streptomyces avermitilis, a soil bacterium, by culturing it in carbon and nitrogen sources (including glycerol, starch, glucose, casein, nitrate, etc.). The process is further carried out by extraction and purification, leading to the formation of avermectin as an intermediate. The intermediate is further hydrogenated in the presence of a catalyst, i.e., chlorotic (triphenylphosphine) rhodium(I). The process results in the production of ivermectin as the final product.
Ivermectin is an antibiotic prepared by fermenting Streptomyces avermitilis bacterium. The nitrogen and carbon sources (including glucose, starch, glycerol, casein, etc.) used for the fermentation of Streptomyces avermitilis serve as the primary feedstocks for ivermectin. The procurement of ivermectin is majorly dependent upon some of the crucial factors, including the availability of its raw materials (including casein, starch, glycerol, etc.), production and processing cost of ivermectin, variations in the market prices and governmental policies, etc. Additionally, other factors, including the demand for ivermectin in the pharmaceutical and healthcare sectors, supply chain stability, trade and transportation activities, and financial conditions, significantly determine its procurement globally.
The project economic analysis provided in the report discusses a Germany-based plant:
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