Mannitol Production By Hydrogenation Reaction

Last Updated: 13-August-2026

Mannitol Production Cost Breakup By Hydrogenation Reaction

This study analyzes Mannitol Production By Hydrogenation Reaction, covering manufacturing, process flow, operating expenses, and financial considerations.

This report provides an extensive cost evaluation of mannitol production by hydrogenation reaction. The production process of mannitol, specifically d-mannitol begins with the chemical reaction between d-fructose and d-glucose under controlled conditions. The reaction contains a 50:50 mixture of the two compounds, i.e., d-fructose and d-glucose, in the presence of Raney nickel catalyst. The process is carried at an elevated temperature ranging between 120 to 160 °C and a high pressure approximately at 70 to 140 atm. It results in the hydrogenation of the mixture and yields d-mannitol, or mannitol as the final product.

Top Producers of Mannitol

  • EMD Millipore
  • Shandong Lianmeng Chemical Group
  • Roquette
  • Cargill
  • ZuChem

Feedstocks for Mannitol

Mannitol is an organic chemical compound that is obtained by using fructose, glucose, and hydrogen as its major feedstocks. The procurement of mannitol and its feedstocks is influenced by different factors. Some of the primary factors include production cost, market prices, and supply chain stability, along with demand from the downstream food, chemical, beverages, and pharmaceutical industries. Additionally, other major factors such as availability of the raw materials (including starch, sucrose, and more), activities in the upstream industries, transportation, trading activities, logistics, and economic conditions altogether help in determining its overall procurement on a large scale.

The project economic analysis provided in the report discusses a Germany-based plant:

  • Manufacturing Process
    • Process Flow
    • Material Flow
    • Material Balance
  • Raw Material and Product's Specifications
    • Raw Material Consumption
    • Product and Co-Product Generation
    • Capital Investment
  • Land and Site Cost
    • Offsites/Civil Works
    • Equipment Cost
    • Auxiliary Equipment Cost
    • Contingency
    • Engineering and Consulting Charges
    • Working Capital
  • Variable Cost
    • Raw Material
    • Utilities
  • Fixed Cost
    • Labor Requirement & Wages
    • Overhead Expenses
    • Maintenance Charges
  • Financing Costs
    • Interest on Working Capital
    • Interest on Loans
  • Depreciation Charges
  • General Sales and Admin Costs
  • Production Cost Summary

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About the Author

Vishakha Agrawal profile photo

Vishakha Agrawal

Lead - Social & Development Research

Delivering procurement intelligence and supply chain analytics across healthcare, FMCG, and chemicals sectors, with expertise in cost modeling, vendor mapping, and spend optimization to support data-driven sourcing decisions and procurement outcomes.

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  • Executive Summary
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  • Techno-Economic Parameters
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  • Executive Summary
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  • Construction Cost Breakdown
  • Equipment Cost Breakdown
  • Techno-Economic Parameters
  • Delivery Format
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  • Executive Summary
  • Key Process Information
  • Variable Cost Breakdown
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  • Capital Investment Analysis
  • Land and Site Cost Details
  • Construction Cost Breakdown
  • Equipment Cost Breakdown
  • Techno-Economic Parameters
  • Delivery Format

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