Production Cost Report | Chemicals

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Phenylpropanolamine Production Cost Breakup By Catalytic Hydrogenation Reaction

Details: Germany - based plant Q2 2024  | From $ USD

This report provides an extensive cost evaluation of phenylpropanolamine production by catalytic hydrogenation reaction. The production process begins with the chemical reaction between benzaldehyde and nitroethane in an alcoholic medium (here, 95% ethanol is used) in the presence of sodium hydroxide.

The reaction results in the production of α-(1-nitroethyl) benzyl alcohol as an intermediate. The intermediate is further reduced through a catalytic hydrogenation reaction, which reduces the nitro-alcohol to its corresponding amine. In this reaction, α-(1-nitroethyl) benzyl alcohol is hydrogenated in the presence of a metal catalyst (such as platinum) and results in the formation of phenylpropanolamine as the final product.

Top Producers of Phenylpropanolamine

  • Riemser Pharma
  • Eipico
  • Abbott
  • Gräub
  • Helicon

Feedstock for Phenylpropanolamine

Phenylpropanolamine is a pharmaceutical compound obtained by using benzaldehyde and nitroethane as its major feedstock. The procurement of phenylpropanolamine is mainly dependent upon some of the crucial factors, including the availability and production cost of its raw materials (including toluene, hydrogen, ethanol, and nitric acid, etc., for nitroethane and benzaldehyde production), as well as the variations in its market prices, logistics, governmental policies, etc. Moreover, other important aspects, such as its demand observed in the pharmaceutical industry, trading and transportation activities, along with governmental and health policies altogether, have a major impact on its procurement process.

The project economic analysis provided in the report discusses a Germany-based plant:

  • Manufacturing Process
    • Process Flow
    • Material Flow
    • Material Balance
  • Raw Material and Product's Specifications
    • Raw Material Consumption
    • Product and Co-Product Generation
    • Capital Investment
  • Land and Site Cost
    • Offsites/Civil Works
    • Equipment Cost
    • Auxiliary Equipment Cost
    • Contingency
    • Engineering and Consulting Charges
    • Working Capital
  • Variable Cost
    • Raw Material
    • Utilities
  • Fixed Cost
    • Labor Requirement & Wages
    • Overhead Expenses
    • Maintenance Charges
  • Financing Costs
    • Interest on Working Capital
    • Interest on Loans
  • Depreciation Charges
  • General Sales and Admin Costs
  • Production Cost Summary
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Report Content

Key Process Information

Evaluation of significant technical parameters along with process descriptions such as:

  • Consumption of Raw Material
  • Product Creation
  • Block Flow Diagram
  • Description of the Manufacturing Facility

Utilities Consumption

Evaluation of utilities consumed during the entire process based on:

  • Consumption per unit of product generated
  • Utility cost split and share of each utility in the total cost

Process Flow Diagram

Representation of various operations involved including:

  • Step-wise process
  • Utility consumption in each operation

Capital Cost Analysis

In-depth analysis of costs involved in setting up a new manufacturing unit, including:

  • Cost of Building a Process Unit
  • Cost of Setting Up the Infrastructure
  • Working Capital
  • Commissioning & Start-Up of the Plant

Implementation Schedule

Time frame of the project design, which includes:

  • Plant Start-Up
  • Plant Construction
  • Engineering Fundamentals
  • Raw Material Procurement

Construction Cost Details

Detailed analysis of costs involved in the operation of various functional units in the process unit and infrastructure.

Operating Cost Analysis

Evaluation of costs associated with the production of the final product, namely:

  • Procurement of Raw Materials
  • Consumption of Utilities
  • Fixed Costs
  • Depreciation

Economic Analysis

Analysis of the way in which process economics are impacted by plant capacity.

  • Construction Cost
  • Working Capital
  • Fixed and Variable Operating Costs
  • Corporate Overhead
  • Depreciation

Customized Analyses

Detailed cost estimates of any industrial plant depending on your requirements, including plant capacity and location as per the need.

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