
This report presents a detailed cost analysis of synthetic menthol production from myrcene using a process involving asymmetric synthesis.
Last Updated: January, 2025
This report presents a detailed cost analysis of synthetic menthol production from myrcene using a process involving asymmetric synthesis. In this process, firstly, an allylic amine is produced from myrcene, which undergoes hydrolysis process followed by asymmetric isomerisation using a BINAP rhodium complex to produce R-citronellal (which is enantiomerically pure). This is further cyclised through a carbonyl-ene-reaction started using zinc bromide to produce isopulegol. The isopulegol produced is finally hydrogenated to obtain synthetic menthol as the final product.
The project economic analysis provided in the report discusses a Germany-based plant:
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