The report provides a detailed analysis essential for establishing an Andrographis paniculata extract production plant. It encompasses all critical aspects necessary for Andrographis paniculata extract production, including the cost of Andrographis paniculata extract production, Andrographis paniculata extract plant cost, Andrographis paniculata extract production costs, and the overall Andrographis paniculata extract production plant cost.
Additionally, the study covers specific expenditures associated with setting up and operating an Andrographis paniculata extract production plant. These encompass production processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.
Andrographis paniculata extract is derived from the leaves and stems of the Green Chiretta plant (Andrographis paniculata). It is used as a traditional medicine for treating respiratory infections, colds, flu, fever, sore throat, and sinusitis. It has immune-boosting and anti-inflammatory effects, with modern formulations helping to improve relief and recovery time.
Its rich andrographolide content drives pharmaceutical uses as an antiviral, antibacterial, and antifungal agent against pathogens causing upper respiratory tract infections, malaria, and skin disorders. It has antidiabetic properties that lower blood glucose in hyperglycemia models. It shows anticancer activity, preventing tumour growth via anti-angiogenic and pro-apoptotic mechanisms. It has hepatoprotective benefits for liver disorders and jaundice, and antioxidant protection against oxidative stress.
The market for Andrographis paniculata extract is influenced by the demand for natural herbal supplements. Its utilisation to manage respiratory infections and chronic ailments contributes to its market growth. The rise in its pharmaceutical and nutraceutical adoption, along with clinical evidence and traditional integration into modern healthcare, fuels its market. The growth in E-commerce and improved extraction innovations expands its applications.
The industrial Andrographis paniculata extract procurement is affected by raw material availability because of seasonal harvests and weather variability. Other factors, like the need for rigorous NIR and HPLC assays for bioactive standardisation, regulatory compliance for quality and safety in supplements and pharma, affect its sourcing.
Raw Material for Andrographis Paniculata Extract Production
According to the Andrographis paniculata extract production plant project report, the key raw materials used in the production of Andrographis paniculata extract include dried Andrographis paniculata aerial parts and leaves, and ethanol.
Production Process of Andrographis Paniculata Extract
The extensive Andrographis paniculata extract production cost report consists of the following major industrial production process:
- By Extraction: The production process of Andrographis paniculata extract starts with pulverising dried aerial parts of the plant into superfine powder using ball milling. The powder goes through percolation extraction with ethanol without heating. The resulting extract is filtered through a microfiltration membrane to remove insoluble residues. This is followed by purification using activated carbon fibre and spray dries to yield pure Andrographis paniculata extract.
Andrographis paniculata extract appears as a green to yellowish-brown powder or viscous liquid, depending on the extraction solvent. It has a bitter taste, a slight aromatic odour, and fluorescence properties varying under UV light. It shows high alcohol-soluble extractive values (up to 23.42%), moderate water-soluble (around 12%), and low petroleum ether-soluble (around 11%). The pH of its 1% aqueous solution is near neutral to slightly acidic. It is rich in bioactive diterpenoids like andrographolide, neoandrographolide, and dehydroandrographolide, along with flavonoids, polyphenols, alkaloids, tannins, and flavanols. All these properties contribute to its anti-inflammatory, antibacterial, antioxidant, hepatoprotective, and anticancer action.