Product Overview

The report provides a detailed analysis essential for establishing a daprodustat production plant. It encompasses all critical aspects necessary for daprodustat production, including the cost of daprodustat production, daprodustat plant cost, daprodustat production costs, and the overall daprodustat production plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a daprodustat production plant. These encompass production processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.

Daprodustat is a pharmaceutical drug used in the healthcare industry for the treatment of anaemia linked to chronic kidney disease. It works by stimulating the body to produce more erythropoietin, which helps increase red blood cell production. It is taken orally and is commonly used as an alternative to injectable anaemia treatments, especially in patients undergoing long-term kidney care.

It is especially useful for patients who are on dialysis or those who are not yet receiving it. It is mainly prescribed to increase haemoglobin levels in patients with reduced red blood cell production. It is also used as a reference compound in research studies for exploring its role in reducing the need for injectable therapies and improving patient comfort through oral administration.

The demand for daprodustat is driven by its application as an oral treatment for anaemia in people with chronic kidney disease (CKD), which boosts its market growth. Its application as a medication in the treatment of anaemia due to chronic kidney disease in adults who have been receiving dialysis also promotes its demand in the pharmaceutical industry. Its demand in the nephrology and healthcare sectors to reduce the need for blood transfusions and maintain stable blood counts in patients with CKD-related anaemia also boosts its market growth. Its demand in the medical research industry to support improved patient care and advances in anaemia management therapies also fuels its market expansion.

The increasing global burden of CKD and the need for convenient, long-term anaemia management solutions significantly boost its rising demand. Additionally, industrial daprodustat procurement depends on factors such as the availability of active pharmaceutical ingredients (APIs), compliance with evolving regulatory frameworks, clinical trial outcomes, and cost-effective production practices. Further, advancements in drug formulation, strategic partnerships among suppliers, and optimised distribution networks also impact its market trends and procurement strategies.

Raw Material for Daprodustat Production

According to the daprodustat production plant project report, the major raw materials for daprodustat production include dicyclohexylcarbodiimide (DCC), malonic acid, and ethyl isocyanoacetate.

Production Process of Daprodustat

The extensive daprodustat production cost report consists of the following industrial production process:

  1. Production from Malonic Acid: The production process of daprodustat begins with the reaction of dicyclohexylcarbodiimide (DCC) with malonic acid to form a cyclic urea intermediate through a modified Biginelli-type reaction. Then, this intermediate (pyrimidine trione) is treated under alkaline conditions with ethylisocyanoacetate, which leads to the formation of a penultimate compound. Finally, this compound undergoes saponification to form daprodustat as the desired product.

Daprodustat is a reversible hypoxia-inducible factor prolyl hydroxylase inhibitor used for the treatment of anaemia due to chronic kidney disease in adults. It appears as a white to off-white crystalline powder that is poorly soluble in water but soluble in dimethyl sulfoxide at approximately 3 milligrams per millilitre. The molecular formula of the compound is C19H27N3O6, and its molecular mass is 393.43 g/mol. The melting point of the compound ranges from 237 to 241 degree Celsius, and it has a density of around 1.359 g/cm3. The most common adverse effects include hypertension, thrombotic vascular events, abdominal pain, dizziness, headache, nausea, and allergic reactions. The compound carries a boxed warning for increased risk of death, myocardial infarction, stroke, and thromboembolism, particularly when used to increase haemoglobin levels to near normal values found in healthy individuals. It is advised to use the compound with caution in patients with a history of cardiovascular disease or malignancy. The recommended dosage ranges from 1 to 24 milligrams administered orally once daily with or without food, with dose adjustments based on haemoglobin response and tolerability.

Daprodustat Production Cost Report

Daprodustat Production Cost Reports

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Product Details

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Product Details

Particulars Details
Product Name Daprodustat
Scope Production Process: Process Flow, Material Flow, Material Balance

Raw Material and Product Specifications: Raw Material Consumption, Product and Co-product Generation

Land and Site Cost: Offsites/Civil Works, Equipment Cost, Auxiliary Equipment Costs, Contingency, Engineering and Consulting Charges, Working Capital

Variable Cost: Raw Material, Utilities, Other Variable Costs

Fixed Cost: Labor Requirements and Wages, Overhead Expenses, Maintenance Charges, Other Fixed Costs

Financing Costs: Interest on Working Capital, Interest on Loans

Other Costs: Depreciation Charges, General Sales and Admin Cost
Currency US$ (Data can also be provided in the local currency)
Pricing and Purchase Options Basic: US$ 2499
Premium: US$ 3499
Enterprise: US$ 4799
Customization Scope The report can be customized as per the requirement of the customer
Post-Sale Analysts Report 10-12 weeks of post-purchase analyst support after report delivery for any queries from the deliverable
Delivery Format PDF and Excel format through email (editable version in PPT/Word format of the report can be also provided on special request)

How does our Daprodustat Production Cost Report Provide Exhaustive Data and Extensive Insights?

At Procurement Resource, we not only focus on optimizing the should cost of production for daprodustat but also provide our clients with extensive intel and rigorous information on every aspect of the production process. By utilizing a comprehensive cost model, we help you break down expenses related to raw materials, labor, and technology, offering clear pathways to savings. We also assist in evaluating the capital expenditure (CAPEX) and operating expenses (OPEX), which are often measured as cost per unit of production, such as USD/MT, ensuring that your financial planning is aligned with industry benchmarks.

 We offer valuable insights on the top technology providers, in-depth supplier database, and best manufacturers, helping you make informed decisions to improve efficiency. Additionally, we design the most feasible layout for your production needs, ensuring the entire process runs smoothly. By minimizing the cash cost of production, we ensure that you stay competitive while securing long-term profitability in the growing daprodustat market. Partnering with Procurement Resource guarantees that every aspect of your production is cost-efficient, advanced, and tailored to your specific requirements.

Key Questions Answered in This Report:

  • What are the key requirements for setting up a daprodustat production plant?
  • How is daprodustat manufactured?
  • What is the process flow involved in producing daprodustat?
  • What are the raw material requirements and costs for producing daprodustat?
  • What is the total size of land required for setting up a daprodustat production plant?
  • What are the construction requirements for setting up a daprodustat production plant?
  • What are the machinery requirements for producing daprodustat?
  • What are the utility requirements and costs for producing daprodustat?
  • What are the manpower requirements for producing daprodustat?
  • What are the average salaries/wages of manpower working in a daprodustat production plant?
  • What are the packaging requirements and associated costs for daprodustat?
  • What are the transportation requirements and associated costs for daprodustat?
  • What are the capital costs for setting up a daprodustat production plant?
  • What are the operating costs for setting up a daprodustat production plant?
  • What should be the price of daprodustat?
  • What will be the income and expenditures for a daprodustat production plant?

About the Author

Vishakha Agrawal profile photo

Vishakha Agrawal

Lead - Social & Development Research

Delivering procurement intelligence and supply chain analytics across healthcare, FMCG, and chemicals sectors, with expertise in cost modeling, vendor mapping, and spend optimization to support data-driven sourcing decisions and procurement outcomes.

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