The report provides a detailed analysis essential for establishing a Meclofenamic Acid production plant. It encompasses all critical aspects necessary for Meclofenamic Acid production, including the cost of Meclofenamic Acid production, Meclofenamic Acid plant cost, Meclofenamic Acid production costs, and the overall Meclofenamic Acid production plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Meclofenamic Acid production plant. These encompass production processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.
Meclofenamic Acid is an FDA-approved non-steroidal anti-inflammatory drug that is widely known for its antipyretic activities. The compound is widely used for the treatment of mild to moderate pain associated with certain joint disorders. Moreover, it is also utilized for the treatment of acute and chronic rheumatoid arthritis, and osteoarthritis. Additionally, it is often employed as the sodium salt for the alleviation of pain in conditions like dysmenorrhoea (painful periods).
The market for Meclofenamic Acid is predominantly driven due to its key role as a an antirheumatic drug for the treatment of rheumatoid arthritis and osteoarthritis, which remarkably increases its demand in the pharmaceutical industry. Moreover, its application as a medication for alleviating menstrual pain and symptoms associated with musculoskeletal and joint disorders further promotes its demand in the healthcare and pharmaceutical industry. Additionally, certain factors, such as its application as a pain relief medication, the availability and cost of raw materials (potassium 2-bromobenzoate, etc.), pricing, compliance with healthcare regulations, scientific advancements, and quality standards, greatly influence industrial Meclofenamic Acid procurement worldwide.
Raw Material for Meclofenamic Acid Production
According to the Meclofenamic Acid production plant project report, the major raw materials for Meclofenamic Acid production include Potassium 2-bromobenzoate and 2,6-dichloro-3-methylaniline.
Production Process of Meclofenamic Acid
The extensive Meclofenamic Acid production cost report consists of the following industrial production process:
- Production from Potassium 2-bromobenzoate: This method of production is initiated by the chemical reaction of the potassium salt of 2-bromobenzoic acid (potassium 2-bromobenzoate) with 2,6-dichloro-3-methylaniline in the presence of copper (II) bromide and using a mixture of N-ethylmorpholine and diglyme (diethylene glycol dimethyl ether) as a solvent, which results in the formation of N-(2,6-dichloro-m-tolyl)anthranylic acid or Meclofenamic acid as the final product.
Meclofenamic Acid is a type of aminobenzoic acid that is mainly sold as a drug under the trade name Meclomen or Meclodol. The molecular formula of the compound is C14H11Cl2N02, and its molar mass is 296.1 g/mol. The compound is used as a sodium salt that serves as a non-steroidal anti-inflammatory drug. Moreover, the IUPAC name of the compound is 2-(2,6-dichloro-3-methylanilino)benzoic acid. The boiling point of the compound is 399.4°C, and its melting point ranges between 257-259°C. Additionally, the density of the compound is 1.3567g/cm3, and it is stored in refrigerator. The compound’s dissociation constant value (pka) is 4.0, and it is practically insoluble in water but is slightly soluble in chloroform and methanol.
