The report provides a detailed analysis essential for establishing a Piroxicam (Feldene) production plant. It encompasses all critical aspects necessary for Piroxicam (Feldene) production, including the cost of Piroxicam (Feldene) production, Piroxicam (Feldene) plant cost, Piroxicam (Feldene) production costs, and the overall Piroxicam (Feldene) production plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Piroxicam (Feldene) production plant. These encompass production processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.
Piroxicam (Feldene) is a synthetic nonsteroidal anti-inflammatory drug (NSAID) that is extensively used in the pharmaceutical industry to manage pain. The compound manly finds its wide usage for therapeutic applications in patients with chronic arthritis. Moreover, it is also utilized as a medicine to alleviate pain and inflammation that is caused by various body conditions, which include rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. Additionally, it is also used to reduce stiffness, pain, and swelling in joints and muscles in patients with certain inflammatory conditions.
The market of Piroxicam (Feldene) is largely led by its application as an analgesic drug for the treatment of inflammation and pain associated with various body conditions, including osteoarthritis and rheumatoid arthritis, remarkably propels its demand in the pharmaceutical industry. Additionally, its application as a medicine to relieve stiffness, swelling, and pain in patients with certain musculoskeletal disorders due to its anti-inflammatory activities further enhances its demand in the medical and pharmaceutical industries. Furthermore, several factors largely influence industrial Piroxicam (Feldene) procurement, such as the availability of raw materials (2-aminopyridine, etc.), cost and pricing, compliance with pharmaceutical regulations, quality standards, technological advancements, environmental considerations, sustainability practices, distribution (including trading and shipping), logistics, safety standards, etc.
Raw Material for Piroxicam (Feldene) Production
According to the Piroxicam (Feldene) production plant project report, the major raw materials for Piroxicam (Feldene) production include 1,1-Dioxide 3-methoxycarbonyl-3,4-dihydro-2-H-1,2-benzothiazine-4-one - 2-Aminopyridine.
Production Process of Piroxicam (Feldene)
The extensive Piroxicam (Feldene) production cost report consists of the following industrial production process:
- Production via Amidation: This method of production involves the amidation of 1,1-dioxide 3-methoxycarbonyl-3,4-dihydro-2-H-1,2-benzothiazine-4-one with 2-aminopyridine, which results in the formation of piroxicam as the final product. In this method, the first step of the reaction involves the conversion of the methoxycarbonyl group into a carboxamide group through the amidation reaction, followed by the second step, which involves the formation of an amide bond between the carboxamide group of the benzothiazine on reaction with 2-aminopyridine and synthesizes piroxicam as the final product.
Piroxicam (Feldene) is a cyclooxygenase-inhibiting drug that is one of the members of Oxicams and belongs to the family of benzothiazine. It is mainly adminitered in the form of oral tablets. The molecular formula of the compound is C15H13N3O4S, and its molecular weight is 331.3 g/mol. The IUPAC name of the compound is 4-hydroxy-2-methyl-1,1-dioxo-N-pyridin-2-yl-1λ6,2-benzothiazine-3-carboxamide. It is majorly recognized by the name Feldene. The melting point of the compound is around 198-200 °C. It is an NSAID that is commonly used for the treatment of osteoarthritis and rheumatoid arthritis.
