Asia
The second half of 2024 saw Asian Acetaminophen prices following a bearish trend, particularly in China, the region's largest producer. July started with a brief price surge due to increased global demand and supply chain disruptions, but this uptick was short-lived. From August through September, the market experienced consistent price declines due to oversupply conditions and reduced demand from downstream pharmaceutical industries.
Chinese manufacturers faced additional pressure from high inventory levels and the appreciation of the Yuan against the USD, which affected export competitiveness. The monsoon season further complicated storage situations, leading to aggressive destocking by suppliers.
Europe
The European Acetaminophen market displayed significant volatility during H2’24. The third quarter began with declining prices as manufacturers worked to clear excess inventories amid reduced demand. However, mid-quarter maintenance shutdowns at key production facilities and increased energy costs led to a temporary price rebound. The fourth quarter saw prices stabilizing at lower levels, influenced by improved logistics at major European ports and the Euro's strength against the USD. German buyers maintained a cautious approach, preferring to purchase on a need-basis rather than building substantial inventories.
North America
North American markets experienced a roller-coaster ride in H2’24. The period began with declining prices due to oversupply and reduced demand from pharmaceutical companies. However, supply chain disruptions and increased global demand caused a brief price surge in the middle of Q3. The market then shifted back to a downward trend as domestic manufacturers increased production and buyers postponed purchases in anticipation of further price declines. The fourth quarter saw continued pressure on prices as companies actively worked to reduce their inventory levels amid weakening demand.
Analyst Insight
According to Procurement Resource, the Acetaminophen market is expected to gradually stabilize in the coming months as supply-demand dynamics reach equilibrium. However, ongoing geopolitical tensions and potential logistics challenges could introduce new volatility to the market.
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Asia
In Asia, a critical production and export hub for acetaminophen, prices experienced a continued decline throughout the second quarter of 2024. Several factors contributed to this downward trend, including an oversupply situation driven by traders actively reducing inventories to make room for new stock. A reduction in local consumption further intensified the market's downward movement, compounded by persistent supply chain issues.
Scheduled plant shutdowns, particularly those occurring from late June to July, prompted manufacturers to offload existing stocks to avoid potential losses, especially for heat-sensitive powdered Acetaminophen that is vulnerable to moisture damage during the approaching monsoon season. Geopolitical tensions also played a role by hampering trade flows and limiting cargo availability, resulting in slower shipments and a decline in demand from both domestic and international markets. The stagnant prices of para-aminophenol, a critical raw material for Acetaminophen production, due to oversupply and muted demand, further exerted downward pressure on Acetaminophen prices in the region.
Europe
In Europe, the price of acetaminophen trended downward, mirroring the developments in key exporting regions like Asia. The European markets were affected by similar factors, including the global oversupply of Acetaminophen and a reduction in inquiries from international markets. Market participants in Europe adopted a cautious approach, anticipating further price decreases and opting to destock their inventories to avoid potential losses. Additionally, easing geopolitical tensions during the second quarter helped reduce freight charges and shipping costs, further contributing to the decline in Acetaminophen prices. The increased shipment momentum and alleviation of container shortages supported this downward trend, leading to a weakened market environment for Acetaminophen.
North America
In North America, the acetaminophen market followed a similar trajectory as the European and Asian countries, with prices declining steadily over the second quarter of 2024. The region witnessed a decline in demand influenced by the global oversupply situation and reduced inquiries from international buyers. The market players in North America also began to stock their domestic inventories, reflecting a cautious approach and contributing to the weakened market sentiment. Furthermore, the easing of geopolitical tensions and subsequent reduction in shipping costs, along with improved shipment flows, played a role in sustaining the downward price trend.
Acetaminophen is a p-aminophenol derivative that functions as an analgesic and antipyretic. Although the specific mechanism by which acetaminophen exerts its effects is unknown, it is thought that it inhibits the nitric oxide (NO) pathway, which is mediated by a number of neurotransmitter receptors including N-methyl-D-aspartate (NMDA) and substance P, and so raises the pain threshold. The antipyretic efficacy might be due to reduction of prostaglandin production and release in the CNS, as well as prostaglandin-mediated effects on the anterior hypothalamic heat-regulating area.
HOC6H4NHCOCH3
Chemical, Pharmaceutical
Paracetamol, 4-Acetamidophenol, 103-90-2, N-(4-Hydroxyphenyl)acetamide
Abbott, Janssen Pharmaceuticals, Bristol-Myers Squibb and Company, Cardinal Health Inc, Viatris, Procter & Gamble Company
CurrencyUS$ (Data can also be provided in local currency)
Supplier Database AvailabilityYes
Customization ScopeThe report can be customized as per the requirements of the customer
Post-Sale Analyst Support360-degree analyst support after report delivery
Note: Our supplier search experts can assist your procurement teams in compiling and validating a list of suppliers indicating they have products, services, and capabilities that meet your company's needs.
The ortho-nitrotoluene is removed during the steam distillation process, leaving the para-nitrotoluene intact for further processing. The para-nitrotoluene is then reduced to the p-amino group, which is followed by acetylation, resulting in acetaminophen.
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