The report provides a detailed analysis essential for establishing a Piroctone Olamine production plant. It encompasses all critical aspects necessary for Piroctone Olamine production, including the cost of Piroctone Olamine production, Piroctone Olamine plant cost, Piroctone Olamine production costs, and the overall Piroctone Olamine production plant cost. Additionally, the study covers specific expenditures associated with setting up and operating a Piroctone Olamine production plant. These encompass production processes, raw material requirements, utility requirements, infrastructure needs, machinery and technology requirements, manpower requirements, packaging requirements, transportation requirements, and more.
Piroctone Olamine is mainly applied in anti-dandruff shampoos and hair care products as it has strong antifungal efficacy to overcome Malassezia globosa, which leads to dandruff. It helps alleviate symptoms such as flaking and irritation while also providing conditioning benefits that enhance hair texture and appearance. Also, Piroctone Olamine is used in pharmaceutical preparations to cure microbial diseases such as seborrheic dermatitis. As a safer alternative to compounds like zinc pyrithione, it has gained popularity following regulatory changes restricting certain ingredients due to environmental concerns.
The market for Piroctone Olamine is driven by its usage in anti-dandruff shampoos and hair products because of its excellent antifungal properties which boosts demand in the personal care and health care industry. The rising cases of dandruff and other scalp conditions is boosting the demand for Piroctone Olamine.
Its use in the formulation of anti-fungal products for managing diseases such as seborrheic dermatitis enhances the market demand of the product in the pharmaceutical and medical sectors. Overall, industrial Piroctone Olamine procurement is influenced by its application in various industries such as personal care and healthcare, and pharmaceutical and medical industries, the rising cases of dandruff and other scalp conditions, the availability of its raw materials (3-methylbut-2-enoic acid and methanol), the cost of its raw materials, changes in lifestyle, safer alternative to traditional agents, and expansion of e-commerce.
Raw Material for Piroctone Olamine Production
According to the Piroctone Olamine production plant project report, the key raw materials used in the production of Piroctone Olamine include 3-methylbut-2-enoic acid and methanol.
Production Process of Piroctone Olamine
The extensive Piroctone Olamine production cost report consists of the following major industrial production process:
- Production from 3-methylbut-2-enoic and Methanol: The production process of Piroctone Olamine involves a five-step procedure. Firstly, 3-methylbut-2-enoic acid is condensed with methanol to form methyl-3,3-dimethylacrylate. This product further reacts with 3,5,5-trimethylhexanoyl chloride in a Friedel-Crafts reaction to yield an intermediate product. The intermediate undergoes cyclization to form a pyrone structure. Subsequently, the pyrone is treated with hydroxylamine sulfate and sodium carbonate, producing an oxime. In the final step, the oxime is converted into Piroctone Olamine through a reaction with ethanolamine, utilizing methanol, ethyl acetate, and activated carbon for solvent management and purification.
Piroctone Olamine is an antibacterial agent and antifungal agent, also called Piroctone Ethanolamine, with the brand name Octopirox. It is an ethanolamine salt of the hydroxamic acid derivative piroctone. The molecular weight of Piroctone Olamine is 298.42 g/mol, and its water solubility is 0.351 mg/mL. The polar surface of Piroctone Olamine is 40.54 Å2, its refractivity is 71.81 m3·mol-1, and its polarizability is 27.69 Å3. The molecular formula of Piroctone Olamine is C14H23NO2.C2H7NO or C16H30N2O3. It has a boiling point of 344.1°C and a melting point of 130-135°C.
