Rifampicin Production from Mixed Carbon Source

This report presents the economics of rifampicin production from mixed carbon sources (peanut meal, soybean flour, glucose, and starch) via a typical fermentation process. In this process, a culture of Nocardia mediterranei is used to inoculate a fermentation media formed by peanut meal, soybean flour, starch, glucose and other compounds. The fermentation produces rifamycin B, which is further processed to rifamycin-O, then to rifamycin-S, then to rifamycin SV, and finally to Rifampicin.

The project economic analysis provided in the report discusses a Germany-based plant:

• Manufacturing Process
  • Process Flow
  • Material Flow
  • Material Balance
• Raw Material and Product's Specifications
  • Raw Material Consumption
  • Product and Co-Product Generation
  • Capital Investment
• Land and Site Cost
  • Offsites/Civil Works
  • Equipment Cost
  • Auxiliary Equipment Cost
  • Contingency
  • Engineering and Consulting Charges
  • Working Capital
• Variable Cost
  • Raw Material
  • Utilities
• Fixed Cost
  • Labor Requirement & Wages
  • Overhead Expenses
  • Maintenance Charges
• Financing Costs
  • Interest on Working Capital
  • Interest on Loans
• Depreciation Charges
• General Sales and Admin Costs
• Production Cost Summary