Isopropylbenzylamine Manufacturing Plant Project Report 2025: Cost Analysis, ROI, and Feasibility Insights

Isopropylbenzylamine Manufacturing Plant Project Report by Procurement Resource thoroughly focuses on every detail that encompasses the cost of manufacturing. Our extensive cost model meticulously covers breaking down Isopropylbenzylamine plant capital cost around raw materials, labour, technology, and manufacturing expenses. This enables precise cost structure optimisation and helps in identifying effective strategies to reduce the overall Isopropylbenzylamine manufacturing plant cost and the cash cost of manufacturing.

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Isopropylbenzylamine (N-Isopropylbenzylamine, C10H15N) is a secondary amine characterised by an isopropyl group and a benzyl group attached to the nitrogen atom. It is a colourless to very slightly yellow, clear liquid with a characteristic amine odour. Isopropylbenzylamine is primarily valued as a speciality chemical intermediate due to its unique sterically hindered amine structure, which makes it useful in specific organic synthesis reactions.
 

Applications of Isopropylbenzylamine (Industry-wise Proportion):

• Pharmaceutical Intermediates (Largest Share): Isopropylbenzylamine can be used as an intermediate in the synthesis of various pharmaceutical compounds and as a precursor for the manufacture of certain drugs. Its specific chemical structure allows for the introduction of a bulky, chiral (if synthesised enantioselectively) alkyl-benzyl amine moiety into more complex molecules.
• Organic Synthesis and Research: It serves as a reagent or ligand in experimental synthesis and novel organic transformations within academic and industrial research laboratories. For example, it can be used as an amine substrate in hydroaminoalkylation reactions.
• Speciality Chemicals: In smaller quantities, it may find use in the production of other fine chemicals where its unique reactivity and steric hindrance are desired.
• Solvent and Stabiliser: In very limited instances, it might act as a stabilising agent in certain chemical reactions or as a specialised solvent.
   

Top 5 Manufacturers of Isopropylbenzylamine

• BOC Sciences
• Cayman Chemical
• Shandong Zhishang Chemical Co., Ltd.
• Shanghai UCHEM Inc.
• Zhengzhou Yichi Technology Co., Ltd.
   

Feedstock for Isopropylbenzylamine and Its Dynamics

The production of Isopropylbenzylamine involves an ammonolysis (alkylation) reaction, using benzyl chloride and isopropylamine as the primary raw materials. The fluctuations in the prices and availability of these feedstock components are crucial for the overall production cost analysis of Isopropylbenzylamine.

• Benzyl Chloride (C6H5CH2Cl): This is a key alkylating agent, derived from petrochemicals.
  • Petrochemical Market: Benzyl chloride is industrially produced by the thermal or photochemical chlorination of toluene. Its price is directly linked to crude oil prices (influencing toluene) and chlorine gas prices (from the energy-intensive chlor-alkali process). Volatility in energy and petrochemical markets directly impacts its cost, affecting the cash cost of production for isopropylbenzylamine.
  • Demand for Derivatives: Benzyl chloride is a significant intermediate for various derivatives like benzyl alcohol (for pharmaceuticals, cosmetics), benzyl cyanide, and quaternary ammonium compounds. High demand from these larger sectors influences its price and availability for Isopropylbenzylamine synthesis.
• Isopropylamine (CH3)2CHNH2): Isopropylamine is primarily produced by the reductive amination of acetone or by the reaction of isopropanol with ammonia.
  • Acetone/Propylene Market: Its price is linked to the petrochemical market, specifically acetone (a co-product of phenol from benzene/propylene) or propylene (for isopropanol). Fluctuations in crude oil and natural gas prices directly impact these precursors.
  • Demand from Agrochemicals/Pharma: Isopropylamine has substantial global demand for agrochemicals (e.g., glyphosate salt), pharmaceuticals, and rubber chemicals. Strong demand from these sectors influences its price and availability for IPBA synthesis.
     

Market Drivers for Isopropylbenzylamine

• Demand for Niche Pharmaceutical Intermediates: The primary market driver for legitimate demand is its role as a specific intermediate in the synthesis of certain active pharmaceutical ingredients (APIs) and other fine chemicals. This demand is driven by ongoing pharmaceutical research and development, and the need for new chemical entities with specific structures that require Isopropylbenzylamine as a precursor. This represents a consistent, albeit limited, industrial procurement by specialised pharmaceutical and chemical companies.
• Organic Synthesis Research: Its use in academic and industrial research for novel organic transformations and material science also contributes to a small but steady demand, as researchers explore new synthetic pathways.
• Structural Properties for Specific Reactions: Isopropylbenzylamine's specific combination of a secondary amine, an isopropyl group, and a benzyl group provides unique steric and electronic properties that can be advantageous in certain condensation or alkylation reactions, driving its use in niche chemical syntheses.
• Geo-locations: Legitimate production and consumption are highly concentrated within countries having advanced fine chemical and pharmaceutical synthesis capabilities, operating under robust regulatory frameworks. Due to global regulatory efforts to curb its illicit diversion, the market is highly fragmented, with strict controls on cross-border trade.
   

Capital Expenditure (CAPEX) for an Isopropylbenzylamine Plant

• Raw Material Storage and Dosing:
  • Benzyl Chloride Storage: Tanks for liquid benzyl chloride. Given its lacrymatory properties and reactivity, storage requires careful ventilation and possibly inert gas blanketing. Accurate dosing pumps.
  • Isopropylamine Storage: Pressurised tanks for liquid isopropylamine (flammable, volatile, pungent), with precise and safe dosing systems.
  • Catalyst Storage & Dosing: If a specific catalyst (e.g., solid acid, phase transfer catalyst) is used, appropriate storage and dosing systems.
• Reaction Section (Core Process Equipment): This constitutes a large portion of the isopropylbenzylamine plant capital cost.
  • Alkylation Reactor: Jacketed, agitated stainless steel or glass-lined reactor designed for the ammonolysis (alkylation) reaction. It must be capable of handling the exothermic reaction, precise temperature control (heating/cooling coils or jackets), and possibly operate under pressure or with reflux. This is a critical piece of machinery directly impacting the Isopropylbenzylamine manufacturing plant cost.
  • Acid Gas Scrubber: The reaction of a haloalkane (benzyl chloride) with an amine (isopropylamine) typically produces acid byproducts (e.g., HCl). A scrubber system (e.g., packed tower with caustic recirculation) is essential to neutralise and capture these acidic off-gases.
• Product Separation and Purification Section:
  • Quench Tanks/Neutralisation: For safely stopping reactions and neutralising acidic mixtures.
  • Phase Separators: For separating organic and aqueous phases after reaction work-up.
  • Distillation Columns: Multiple vacuum distillation columns are crucial for purifying crude Isopropylbenzylamine from unreacted starting materials, byproducts (e.g., di- and tri-alkylated amines), and solvents.
  • Condensers and Reboilers: Essential for distillation.
  • Crystallisers (if applicable): If the product is isolated as a salt (e.g., hydrochloride), crystallisation equipment might be needed.
  • Filtration Units: Filter presses or centrifuges for separating solid impurities or crystalline products.
  • Washing Vessels: For washing the crude product with water or dilute solutions to remove impurities and salts.
• Product Finishing Section:
  • Product Storage Tanks: For purified Isopropylbenzylamine liquid. These should be inerted to prevent oxidation or degradation during storage.
  • Packaging Lines: Automated filling lines for drums or intermediate bulk containers (IBCs), designed for hazardous liquid handling.
• Pumps, Agitators, and Transfer Lines: Corrosion-resistant and explosion-proof pumps, agitators for reactors/tanks, and piping for handling various liquid process streams.
• Piping, Valves, & Instrumentation: Extensive network of pipes, automated valves, sensors, and a robust Distributed Control System (DCS) or PLC for precise temperature, pressure, flow control, and critical safety interlocks, given the handling of flammable and toxic amines and chlorinated compounds.
• Utilities and Offsites Infrastructure:
  • Boilers/Steam Generators: For providing heat to reactors and distillation columns.
  • Cooling Towers/Chillers: For process cooling and condensers.
  • Water Treatment Plant: To ensure high-purity process water for all stages.
  • Effluent Treatment Plant (ETP): Highly specialised ETP for treating wastewater containing organic amines, chlorinated compounds, and inorganic salts. Ensuring stringent environmental compliance is crucial.
  • Air Pollution Control Systems: Advanced scrubbers and activated carbon adsorption units for managing amine odours, solvent vapours, and any gaseous HCl emissions.
  • Electrical Substation and Distribution: Powering all machinery and plant operations.
  • Laboratory & Quality Control Equipment: Gas chromatographs (GC), HPLC, mass spectrometers (MS), and other advanced analytical instruments for raw material testing, in-process control, and final product purity assurance (including trace impurity analysis critical for avoiding illicit substance connotations).
  • Warehouse and Packaging Area: For storing raw materials, intermediates, and finished Isopropylbenzylamine, complying with hazardous goods regulations.
  • Civil Works and Buildings: Land development, foundations for equipment, process buildings, control rooms, administrative offices, and utility buildings, designed with extensive containment and safety features for hazardous chemicals.
  • Safety and Emergency Systems: Comprehensive fire suppression, explosion protection, advanced gas detection (for amines), spill containment, emergency showers/eyewash stations, specialised personal protective equipment (PPE), and robust safety interlock systems due to the flammability and toxicity of reactants and products.

The cumulative sum of these elements determines the comprehensive isopropylbenzylamine plant capital cost, a key metric in the cost model, heavily influenced by safety and environmental compliance investments.
 

Operating Expenses (OPEX) for an Isopropylbenzylamine Plant

• Raw Material Costs (Largest Component):
  • Benzyl Chloride: Its price fluctuations are a major driver of the final cost per metric ton (USD/MT).
  • Isopropylamine: The primary amine feedstock.
  • Catalyst: Consumption and replenishment costs (if applicable).
  • Solvents/Reagents: Costs for initial fill and make-up for losses of solvents, acids, or bases used in work-up and purification.
  • Water: For process, washing, and utility purposes.
• Utility Costs:
  • Electricity: For pumps, agitators, vacuum systems, and general plant operations. High-purity distillation can be energy-intensive.
  • Steam/Heating Fuel: For maintaining reaction temperatures and distillation columns.
  • Cooling Water: For condensers and process cooling.
• Operating Labour Costs:
  • Salaries, wages, benefits, and extensive specialised training costs for skilled chemical operators, maintenance technicians, and supervisory staff. Due to the hazardous nature of the chemicals, safety protocols and compliance efforts significantly increase these manufacturing expenses.
• Maintenance and Repairs:
  • Routine preventative maintenance and repair of reactors, distillation columns, and associated equipment. Managing corrosion from acidic byproducts and general wear and tear is a continuous manufacturing expense.
• Plant Overhead Costs:
  • Administrative salaries (plant management, HR, safety officers, compliance specialists), insurance (likely higher due to hazardous operations and regulatory risks), local property taxes (relevant to the specific global location), legal fees (for compliance and scrutiny), laboratory consumables, enhanced security, and general plant supplies.
• Waste Management and Environmental Compliance Costs (Potentially High):
  • Costs associated with treating and safely disposing of wastewater from the ETP (containing amines, chlorinated organics, salts), managing any gaseous emissions (amine odours, solvent vapours, HCl), and solid residues. Due to the regulatory sensitivity of the product, waste streams are under intense scrutiny, adding significant operating expenses.
• Packaging and Logistics Costs:
  • Cost of specialised drums or IBCs for packaging Isopropylbenzylamine, and higher logistics costs for transporting a hazardous and potentially regulated material.
• Quality Control Costs:
  • Ongoing expenses for rigorous analytical testing (e.g., GC, HPLC, MS) to ensure extreme purity and the absence of specific impurities, crucial for maintaining legitimate status and avoiding any association with illicit substances.
     

Efficient control of both fixed and variable expenses, especially raw material costs, energy consumption, and strict adherence to safety, environmental, and regulatory requirements, is essential to achieving a competitive production cost per metric ton (USD/MT) of Isopropylbenzylamine in a demanding market environment.
 

Manufacturing Process of Isopropylbenzylamine

This report comprises a thorough value chain evaluation for Isopropylbenzylamine manufacturing and consists of an in-depth production cost analysis revolving around industrial Isopropylbenzylamine manufacturing.

The industrial manufacturing process of Isopropylbenzylamine involves an ammonolysis (alkylation) reaction between a chlorinated compound and a primary amine.

• The raw materials for this process include: Benzyl chloride and isopropylamine.The synthesis begins with the chemical reaction of benzyl chloride with isopropylamine. This reaction, a type of nucleophilic substitution (often termed alkylation or ammonolysis in this context), is carried out under controlled conditions, which may involve specific temperature (e.g., 50-150 degree Celsius), pressure, and solvent use, and often in the presence of a catalyst (such as an inorganic base or phase transfer catalyst). During the reaction, the chlorine atom of benzyl chloride is replaced by the isopropylamino group, resulting in the formation of Isopropylbenzylamine as the desired product. Hydrogen chloride (HCl) is generated as a byproduct and is often neutralised. This method further utilises multiple techniques for product recovery and purification, including distillation (often vacuum distillation to separate the product from unreacted starting materials, byproducts like dibenzylated products, and solvents), crystallisation (if solid), and filtration, to achieve high purity levels of Isopropylbenzylamine as the final product.
   

Properties of Isopropylbenzylamine

• Physical State: Clear, colourless to very slightly yellow liquid.
• Odour: Characteristic amine odour (sometimes described as mild, aromatic).
• Chemical Name: N-Benzylpropan-2-amine or N-Isopropylbenzylamine.
• Molecular Formula: C10H15N.
• Molecular Weight: 149.24 g/mol.
• Melting Point: -26 degree Celsius (-15 degree Fahrenheit). It can exist as a solid (hydrochloride salt is crystalline).
• Boiling Point: 200 degree Celsius (392 degree Fahrenheit) at 760 mmHg.
• Density: 0.892 g/mL at 25 degree Celsius (less dense than water).
• Solubility: Slightly soluble in water; readily soluble in organic solvents like ethanol, diethyl ether, and chloroform.
• Flash Point: 70 degree Celsius (158 degree Fahrenheit, closed cup), indicating it is a combustible liquid.
• Vapour Pressure: Relatively low (e.g., 0.1 mmHg at 25 degree Celsius).
• Basicity (pKa): A weak base, pKa approx. 9.77.
• Reactivity: Undergoes typical amine reactions (e.g., acylation, further alkylation); sensitive to strong oxidising agents.
   

Isopropylbenzylamine Manufacturing Plant Report provides you with a detailed assessment of capital investment costs (CAPEX) and operational expenses (OPEX), generally measured as cost per metric ton (USD/MT). This approach ensures that your investment decisions are aligned with the latest industry standards and economic feasibility metrics, enhancing your manufacturing efficiency and financial planning.

Apart from that, this Isopropylbenzylamine manufacturing plant report also covers the leading technology providers that help you plan a robust plan of action related to Isopropylbenzylamine manufacturing plant and its production process, and also by helping you with an in-depth supplier database. This report provides exclusive insights into the best manufacturing practices for Isopropylbenzylamine and technology implementation costs. This report also covers operational cash flow, fixed and variable costs, and detailed break-even point analysis, ensuring that your manufacturing process is not only efficient but also economically viable in the competitive market landscape.

In addition to operational insights, the Isopropylbenzylamine manufacturing plant report also comprehensively focuses on lifecycle cost analysis, maintenance costs, and energy consumption costs, which are critical for maintaining long-term sustainability and profitability. Our manufacturing cost analysis extends to include regulatory compliance costs, inventory holding costs, and logistics and distribution costs, providing a holistic view of the potential expenses and savings.

We at Procurement Resource ensure that this report is not only cost-efficient, environmentally sustainable, and aligned with the latest technological advancements but also that you are equipped with all necessary tools to optimise supply chain operations, manage risks effectively, and achieve superior market positioning for Isopropylbenzylamine.
 

Key Insights and Report Highlights

Key Questions Covered in our Isopropylbenzylamine Manufacturing Plant Report

• How can the cost of producing Isopropylbenzylamine be minimised, cash costs reduced, and manufacturing expenses managed efficiently to maximise overall efficiency?
• What is the estimated Isopropylbenzylamine manufacturing plant cost?
• What are the initial investment and capital expenditure requirements for setting up a Isopropylbenzylamine manufacturing plant, and how do these investments affect economic feasibility and ROI?
• How do we select and integrate technology providers to optimise the production process of Isopropylbenzylamine, and what are the associated implementation costs?
• How can operational cash flow be managed, and what strategies are recommended to balance fixed and variable costs during the operational phase of Isopropylbenzylamine manufacturing?
• How do market price fluctuations impact the profitability and cost per metric ton (USD/MT) for Isopropylbenzylamine, and what pricing strategy adjustments are necessary?
• What are the lifecycle costs and break-even points for Isopropylbenzylamine manufacturing, and which production efficiency metrics are critical for success?
• What strategies are in place to optimise the supply chain and manage inventory, ensuring regulatory compliance and minimising energy consumption costs?
• How can labour efficiency be optimised, and what measures are in place to enhance quality control and minimise material waste?
• What are the logistics and distribution costs, what financial and environmental risks are associated with entering new markets, and how can these be mitigated?
• What are the costs and benefits associated with technology upgrades, modernisation, and protecting intellectual property in Isopropylbenzylamine manufacturing?
• What types of insurance are required, and what are the comprehensive risk mitigation costs for Isopropylbenzylamine manufacturing?