Tryptophan Price Trend and Forecast

Tryptophan Regional Price Overview

Get the latest insights on price movement and trend analysis of Tryptophan in different regions across the world (Asia, Europe, North America, Latin America, and the Middle East & Africa).


Tryptophan Price Trend for the Q1 of 2024

Product Category Region Price Time Period
Tryptophan Healthcare Asia 9365 USD/MT March 2024

Stay updated with the latest Tryptophan prices, historical data, and tailored regional analysis


Tryptophan is an amino acid that is naturally present in various diet components and is used in various pharmaceutical drugs like antidepressants. The fermentation process is primarily employed to produce tryptophan using wild-type or genetically modified bacteria such as B. amyloliquefaciens, C. glutamicum, or E. coli. So, the price trends are usually dependent on the basic nutrient materials like corn starch, glucose, sugar, etc.

Tryptophan Price Chart

Tryptophan Price Trends

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During the first quarter of 2024, tryptophan prices witnessed a slight downturn as the domestic demand declined relatively. Sufficient inventory stocks were primarily responsible for this behavior of prices of tryptophan in the Asian regional markets. The international trade was faced with various challenges at different levels, and the domestic trade alone was not able to sufficiently support the price trajectory. Overall, a very mixed market performance was witnessed.


The demands were even more humble in the European markets compared to the Asian markets. The surge in the logistic and processing costs did provide some positive cost support, however, the easy availability and depreciation in the feedstock prices nullified their impact on the upstream costs. Given these fluctuations in the market drivers, the tryptophan prices followed such a confined trajectory. Majorly because the prices were mostly tugged between these driving factors. Overall, a very average market performance was witnessed.

North America

In the American tryptophan market, the prices were found to be oscillating within a very narrow range. The agriculture sector was undergoing a downfall in the region which depreciated the feedstock prices for tryptophan as well. Rising Houthi attacks in the Red Sea were majorly impacting the trade volumes through the Red Sea. The Somali pirates in the Indian Ocean also started to cause trouble.

Amidst all this, the armed unrest in Europe and the Middle East was still rising with each passing moment, which was creating different kinds of problems for the global trading community. Given these dire situations, the regional markets became more and more dependent on regional trade and consumption volumes. Because of this, the tryptophan prices were also unable to see much fluctuations during the said time.

Analyst Insight

According to Procurement Resource, the macroeconomic indicators suggest that the prices will continue to oscillate in the coming months as well. The market drivers for Tryptophan do not suggest any notable changes going forward.

Tryptophan Price Trend for October - December of 2023


In Asia, particularly China, the Tryptophan price trend in Q4 2023 experienced a noticeable decrease in prices. This trend was largely driven by the decline in corn prices, a key raw material for Tryptophan production. The consistent rise in corn volume in the production area, coupled with the downward trend in its prices, prompted grain trading entities to sell off their stocks. This, in turn, impacted the Tryptophan market, leading to reduced manufacturing costs for Chinese producers.

The market in China was further influenced by subdued domestic and international demand. Official data indicated a deceleration in the manufacturing sector, with a significant decrease in export sales, especially to the USA and European markets. This decline in demand, combined with substantial Tryptophan inventories held by Chinese manufacturers, led to potential discounts offered to clear stock before the year's end.


The European Tryptophan price trend declined during the fourth quarter of 2023. The German economy faced a slight contraction, as reported by the country's central bank, along with an unexpected decline in business confidence. These economic challenges were rooted in heightened energy prices, global economic fragility, and interest rate hikes. Inflationary pressures intensified towards the end of the quarter, with companies reporting a significant surge in output prices.

This increase in costs and the overall economic downturn likely influenced consumer confidence, contributing to a downturn in Tryptophan prices. Given Germany's reliance on imports, particularly from China, the market trend mirrored those observed in the Asian giant.

North America

In North America, particularly the United States, Tryptophan price trend followed downward trajectory in the fourth quarter of 2023. The Federal Reserve's decision to maintain interest rates unchanged since late July influenced consumer spending patterns.

This decision, coupled with the U.S. dollar's strength against the Chinese yuan, potentially encouraged increased imports, supporting the downward trend in Tryptophan prices. However, there was potential for a resurgence in prices at the commencement of FY24, propelled by heightened demand in the food and nutraceutical sectors.

The prospect of rate reductions by central banks in 2024 could stimulate higher consumer spending, thereby fostering positive sentiments in the market. The U.S. market dynamics in Q4 2023 reflected the global trend, with the country adapting to the international supply and demand scenario for Tryptophan.

Analyst Insight

According to Procurement Resource, the global tryptophan price trend is expected to sustain the downward trend in the initial months of 2024. However, the demand landscape could later pull the depreciatory price curve up as the situation improves in 2024.

Tryptophan Price Trend for the July - September of 2023


The condition of the Asian markets was rather grim in the third quarter of 2023 as industrial development slowed down, which had an adverse effect on tryptophan prices. The downstream industries witnessed a significant contraction as the number of new orders and domestic procurement rates slid by a great margin. In addition to this, the overseas industries also lowered their demand for tryptophan, which had an adverse effect on tryptophan price trend. Further, concerns about the slow economic growth of the region also loomed over the manufacturers that kept the tryptophan price trend in the negative zone.


The southwards trajectory of tryptophan prices was based on the depreciation in the downstream market as the customers were hesitant in placing orders in bulk. The inclination in inflation and interest rates and challenging economic conditions also pressured the tryptophan market to move in the negative direction. Additionally, in view of poor demand dynamics, the traders adopted a destocking approach and lowered their price quotations to keep the market away from the red zone.

North America

The new orders and number of inquiries from the downstream industries in both domestic and overseas industries faced a noticeable fall as the North American economy seemed to be undergoing a period of stress. However, the rising cost of energy production and transportation raised the prices of production and helped in the upswing of tryptophan market momentum. Additionally, the imports from Asian countries dipped, lowering the availability of the product in the market causing the tryptophan price trend to turn in an upward direction.

Analyst Insight

According to Procurement Resource, the price trend of Tryptophan are expected to remain bearish as the market is experiencing lower rates of procurement from the downstream industries.

Tryptophan Price Trend for the First Half of 2023


Tryptophan prices exhibited mixed market trend throughout the said period of H1’23. As Tryptophan is used in the pharma sector primarily as an antidepressant, the market fluctuations depended heavily on the downstream demands from the pharma industry. The first quarter was relatively slow as the upstream cost support from the feedstock decreased substantially.

Demands were dull, given the high inventory levels. Suppliers discounted prices in order to facilitate stock movement. These trend continued well in the second quarter too. It was in the latter half of Q2’23 that the inventories started vacating, and the sales queries rose, pushing up the market prices for Tryptophan.


The European Tryptophan market almost replicated the Asian Tryptophan market trend in the first half of the year 2023. Price trend were sluggish for most of the said period. But some improvements were seen in the latter half of the second quarter. A sagging upstream cost, along with normalization in crude oil prices and freight situation, influenced the muted market sentiments of Tryptophan. However, a rise in demand by the end of quarter two inflicted some positivity in the European Tryptophan market.

North America

The North American Tryptophan market could not behave any differently than the other global markets. Owing to the dull demands, the price trend first slid for the majority of the discussed time period and then shifted momentum with increasing demands at the end of the second quarter.

Analyst Insight

According to Procurement Resource, the demand outlook for Tryptophan does not look very promising for the coming months. Further market fluctuations are anticipated.

Procurement Resource provides latest prices of Tryptophan. Each price database is tied to a user-friendly graphing tool dating back to 2014, which provides a range of functionalities: configuration of price series over user defined time period; comparison of product movements across countries; customisation of price currencies and unit; extraction of price data as excel files to be used offline.

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About Tryptophan

Tryptophan is not only found in most proteins, but it also acts as a precursor of serotonin. Tryptophan is converted to 5-hydroxy-tryptophan (5-HTP), which in turn, is converted into serotonin, a neurotransmitter that is also essential in regulating appetite, sleep, mood, as well as pain. Tryptophan is a natural sedative which is present in dairy products, meats, brown rice, fish, and even in soybeans.

Tryptophan Product Details

Report Features Details
Product Name Tryptophan
Chemical Formula C11H12N2O2
Industrial Uses Pharmaceutical Drug, Antidepressant
HS Code 29224990
Molecular Weight 204.22 g/mol
Synonyms (2S)-2-amino-3-(1H-indol-3-yl) propanoic acid, L-Tryptophan, (S)-Tryptophan, 2-Amino-3-(1H-indol-3-yl)propanoic acid
Supplier Database Penta Manufacturing Company, Charkit Chemical Company LLC, Acros Organics
Region/Countries Covered Asia Pacific: China, India, Indonesia, Pakistan, Bangladesh, Japan, Philippines, Vietnam, Iran, Thailand, South Korea, Iraq, Saudi Arabia, Malaysia, Nepal, Taiwan, Sri Lanka, UAE, Israel, Hongkong, Singapore, Oman, Kuwait, Qatar, Australia, and New Zealand

Europe: Germany, France, United Kingdom, Italy,  Spain, Russia, Turkey, Netherlands, Poland, Sweden, Belgium, Austria, Ireland Switzerland, Norway, Denmark, Romania, Finland, Czech Republic, Portugal and Greece

North America: United States and Canada

Latin America: Brazil, Mexico, Argentina, Columbia, Chile, Ecuador, and Peru

Africa: South Africa, Nigeria, Egypt, Algeria, Morocco
Currency US$ (Data can also be provided in local currency)
Supplier Database Availability Yes
Customization Scope The report can be customized as per the requirements of  the customer 
Post-Sale Analyst Support 360-degree analyst support after report delivery

Note: Our supplier search experts can assist your procurement teams in compiling and validating a list of suppliers indicating they have products, services, and capabilities that meet your company's needs.

Tryptophan Production Process

  • Production of Tryptophan via Fermentation

Tryptophan production at industrial level utilises biosynthesis and is based on the fermentation of serine and indole. The process involves the use of either wild-type or genetically modified bacteria such as B. amyloliquefaciens, C. glutamicum or E. coli. These microbial strains carry mutations and the conversion is catalysed by the enzyme tryptophan synthase.


The displayed pricing data is derived through weighted average purchase price, including contract and spot transactions at the specified locations unless otherwise stated. The information provided comes from the compilation and processing of commercial data officially reported for each nation (i.e. government agencies, external trade bodies, and industry publications).

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